2008 East Carolina University Schedule/Results
| Date | Opponent | Location | TV | Outcome/Time |
| 11/14/08 | East Carolina 74, Hampton 58 | Greenville, N.C. | | 4:30 p.m.
Gametracker |
| 11/18/08 | East Carolina 80, Appalachian State 75 | Greenville, N.C. | | 6:00 p.m.
Gametracker |
| 11/21/08 | Presbyterian at East Carolina | Greenville, N.C. | | 6:00 p.m. CT
Gametracker |
| 11/25/08 | East Carolina at VCU | Richmond, Va. | | 6:00 p.m. CT |
| 11/28/08 | North Carolina Central at East Carolina
Lady Pirates Invitational | Greenville, N.C. | | 4:00 p.m. CT
Gametracker |
| 11/29/08 | East Carolina vs. Buffalo / North Carolina A&T
Lady Pirates Invitational | Greenville, N.C. | | TBA
Gametracker |
| 12/06/08 | East Carolina at Virginia | Charlottesville, Va. | | 1:00 p.m. CT |
| 12/14/08 | East Carolina at UNC-Wilmington | Wilmington, N.C. | | 3:00 p.m. CT |
| 12/16/08 | East Carolina vs. Gardner-Webb | Greenville, N.C. | | 6:00 p.m. CT
Gametracker |
| 12/19/08 | East Carolina vs. Mercer
Bahamas Splash Shootout | Nassau, Bahamas | | 7:00 p.m. CT |
| 12/20/08 | East Carolina vs. Florida Atlantic
Bahamas Splash Shootout | Nassau, Bahamas | | 3:00 p.m. CT |
| 12/29/08 | East Carolina vs. Marist
FIU Tournament | Miami, Fla. | | 6:00 p.m. CT |
| 12/30/08 | East Carolina vs. Florida International/Georgia Southern
FIU Tournament | Miami, Fla. | | TBA |
| 01/03/09 | Marshall at East Carolina | Greenville, N.C. | | 1:00 p.m. CT |
| 01/08/09 | East Carolina at Tulsa | Tulsa, Okla. | | 7:00 p.m. CT |
| 01/10/09 | East Carolina at SMU | Dallas, Texas | | 2:00 p.m. CT |
| 01/18/09 | East Carolina at Marshall | Huntington, W.Va. | | 1:00 p.m. CT |
| 01/22/09 | Memphis at East Carolina | Greenville, N.C. | | 6:00 p.m. CT |
| 01/24/09 | UAB at East Carolina | Greenville, N.C. | | 1:00 p.m. CT |
| 01/29/09 | East Carolina at UCF | Orlando, Fla. | | 6:00 p.m. CT |
| 01/31/09 | East Carolina at Southern Miss | Hattiesburg, Miss. | | 4:00 p.m. CT |
| 02/05/09 | UTEP at East Carolina | Greenville, N.C. | | 6:00 p.m. CT |
| 02/08/09 | East Carolina at Tulane | New Orleans, La. | | 2:00 p.m. CT |
| 02/13/09 | Southern Miss at East Carolina | Greenville, N.C. | | 6:00 p.m. CT |
| 02/15/09 | UCF at East Carolina | Greenville, N.C. | | 1:00 p.m. CT |
| 02/20/09 | East Carolina at Memphis | Memphis, Tenn. | | 7:00 p.m. CT |
| 02/22/09 | East Carolina at UAB | Birmingham, Ala. | | 2:00 p.m. CT |
| 02/26/09 | Rice at East Carolina | Greenville, N.C. | CBS College Sports | 7:00 p.m. CT |
| 02/28/09 | Houston at East Carolina | Greenville, N.C. | | 1:00 p.m. CT |
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